Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7711553 | 0.82 | CYP2C19 (0.32) | — | |
| SCHEMBL7708337 | 0.82 | ALDH1A1 (0.30) | — | |
| SCHEMBL7708012 | 0.82 | KDM4D (0.35) | — | |
| SCHEMBL7708190 | 0.81 | PARP1 (0.38) | EDNRAMEN1KMT2AATM | |
| SCHEMBL7710851 | 0.80 | AAK1 (0.31) | — | |
| SCHEMBL7711384 | 0.80 | EDNRA (0.31) | EDNRAMEN1KMT2AATMBACE1 | |
| SCHEMBL7711069 | 0.80 | CYP3A4 (0.31) | — | |
| SCHEMBL6999701 | 0.78 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL7704892 | 0.72 | — | — | |
| SCHEMBL7710216 | 0.71 | HSD17B10 (0.35) | ALOX5BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365736-B1 | TREATMENT OF NERVOUS SYSTEM DISORDERS, CARDIOVASCULAR DISORDERS AND FOR ACTIVITY AS NO-SYNTHASES (NOS) INHIBITORS. | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-04-02 | — | — | US | disclosed |