SCHEMBL7708394

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8244711	1.00	CHRNA1 (0.35)	CHRNA1CHRNGCHRNB1CHRNB2SLC6A2
	SCHEMBL15467278	1.00	CHRNA1 (0.35)	CHRNA1CHRNGCHRNB1CHRNB2SLC6A2
	SCHEMBL2116071	0.82	KDM1A (0.45)	CHRNA1CHRNB1CHRNB2SLC6A2CHRNB4
	SCHEMBL20859650	0.82	KDM1A (0.45)	CHRNA1CHRNB1CHRNB2SLC6A2CHRNB4
	SCHEMBL20859649	0.82	KDM1A (0.45)	CHRNA1CHRNB1CHRNB2SLC6A2CHRNB4
	SCHEMBL31371272	0.82	KDM1A (0.45)	CHRNA1CHRNB1CHRNB2SLC6A2CHRNB4
	SCHEMBL2474866	0.82	HTR2C (0.38)	CHRNA1CHRNGCHRNB1CHRNB2SLC6A2
	SCHEMBL31351865	0.82	KDM1A (0.45)	CHRNA1CHRNB1CHRNB2SLC6A2CHRNB4
	SCHEMBL21153824	0.80	MAPK1 (0.40)	HSD11B1ALDH1A1SMN1; SMN2MEN1KMT2A
	SCHEMBL1286642	0.80	MAPK1 (0.40)	HSD11B1ALDH1A1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.