Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5621645 | 0.96 | PARP1 (0.75) | PARP1PARP2 | |
| SCHEMBL631280 | 0.91 | PARP1 (1.00) | PARP1PARP2 | |
| SCHEMBL5621588 | 0.89 | PARP1 (0.77) | PARP1PARP2 | |
| SCHEMBL6870302 | 0.88 | PARP1 (0.64) | PARP1PARP2 | |
| SCHEMBL5620067 | 0.87 | PARP1 (0.85) | PARP1PARP2 | |
| SCHEMBL5621502 | 0.87 | PARP1 (0.84) | PARP1PARP2 | |
| SCHEMBL5621575 | 0.87 | PARP1 (0.84) | PARP1PARP2 | |
| SCHEMBL7708440 | 0.86 | PARP1 (0.61) | PARP1PARP2 | |
| SCHEMBL5621356 | 0.85 | PARP1 (0.78) | PARP1PARP2 | |
| SCHEMBL5621376 | 0.85 | PARP1 (0.70) | PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448271-B1 | SUCH AS 2-(PIPERIDIN-4-YL)BENZIMIDAZOLE-4-CARBOXAMIDE; INHIBITORS OF ENZYME POLY(ADP-RIBOSE)POLYMERASE; IMPROVED WATER SOLUBILITY | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-10 | — | — | US | disclosed |