SCHEMBL7708736

SCHEMBL7708736

Cc1cc([CH]c2cc(C)c(O)c(C)c2)cc(C)c1O

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
PTGS1 P23219 13/20 0.54
PTGS2 P35354 13/20 0.54
ALOX5 P09917 12/20 0.54
CYP2C9 P11712 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2B6 P20813 1/20 0.54
TTR P02766 1/20 0.54
EEF2K O00418 1/20 0.50
SRC P12931 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27620481 0.86 PTGS1 (0.70) PTGS1PTGS2ALOX5CYP2C9CYP1A2
SCHEMBL1824103 0.82 PTGS1 (0.74) PTGS1PTGS2ALOX5CYP2C9CYP1A2
SCHEMBL1824102 0.82 PTGS1 (0.74) PTGS1PTGS2ALOX5CYP2C9CYP1A2
SCHEMBL10551448 0.80 CA1 (0.52) CA1CA2PTGS1PTGS2ALOX5
SCHEMBL12982989 0.78 PTGS1 (0.50) CA1CA2PTGS1PTGS2ALOX5
SCHEMBL143965 0.78 CYP2C9 (0.56) CA1CA2PTGS1PTGS2ALOX5
SCHEMBL220820 0.78 PTGS1 (0.50) CA1CA2PTGS1PTGS2ALOX5
SCHEMBL14992948 0.76 PTGS1 (0.59) PTGS1PTGS2ALOX5CYP2C9CYP1A2
SCHEMBL18456965 0.76 MAPT (0.54) CA1CA2PTGS1PTGS2ALOX5
SCHEMBL14173720 0.76 PTGS1 (0.53) CA1CA2PTGS1PTGS2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6358665-B1 ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE CLARIANT INTERNATIONAL LTD. (CH) 2002-03-19 US disclosed
EP-1033624-A1 RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE Clariant International Ltd. (CH) 2000-09-06 EP disclosed