SCHEMBL143965

SCHEMBL143965

Cc1cc(C=O)cc(C)c1O

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2B6 P20813 1/20 0.56
SRC P12931 2/20 0.52
EEF2K O00418 1/20 0.52
ALOX5 P09917 8/20 0.50
PTGS1 P23219 7/20 0.50
PTGS2 P35354 7/20 0.50
TTR P02766 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
ERN1 O75460 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL299751 0.88 EGFR (0.53) CYP2C9CYP1A2CYP3A4CYP2D6CYP2B6
SCHEMBL29459683 0.88 EGFR (0.53) CYP2C9CYP1A2CYP3A4CYP2D6CYP2B6
Benzaldehyde SCHEMBL27604595 0.87 PTGS1 (0.66) CYP2C9CYP1A2CYP3A4CYP2D6CYP2B6
SCHEMBL5646596 0.86 ERN1 (0.56) CYP2C9CYP1A2CYP3A4CYP2D6CYP2B6
SCHEMBL6740604 0.86 ERN1 (0.45) CYP2C9CYP1A2CYP3A4CYP2D6CYP2B6
SCHEMBL12687888 0.84 SRC (0.47) CYP2C9CYP1A2CYP3A4CYP2D6CYP2B6
SCHEMBL670883 0.84 PTGS1 (0.49) CYP2C9CYP1A2CYP3A4CYP2D6CYP2B6
SCHEMBL13851317 0.84 KDM4E (0.54) CYP2C9CYP1A2CYP3A4CYP2D6CYP2B6
SCHEMBL12552996 0.84 ERN1 (0.44) CYP2C9CYP1A2CYP3A4CYP2D6CYP2B6
SCHEMBL12593986 0.84 PTGS1 (0.47) CYP2C9CYP1A2CYP3A4CYP2D6CYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1919 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12351586-B2 Thiophene[2,3-d]pyrimidine derivative DK6-1 and its preparation method and application SHAN DONG UNIVERSITY (CN) 2025-07-08 US claimed
CN-119859280-A Porphyrin pigment derivative and preparation method thereof, low-temperature black photoresist and preparation method and application thereof 西安思摩威新材料有限公司 2025-04-22 CN claimed
CN-116332887-B Synthesis method and application of orange ketone derivatives with nonalcoholic steatohepatitis resistance 天津科技大学 2024-08-13 CN claimed
US-11957793-B2 Nanoparticles SINTEF TTO AS (NO) 2024-04-16 US claimed
WO-2024071594-A1 COMPOSITION COMPRISING QUINAZOLINE SALT COMPOUND FOR TREATMENT OF ARTHRITIS AND PREPARATION METHOD THEREFOR 주식회사 베노바이오 2024-04-04 WO claimed
CN-112584824-B Nanoparticles 新泰福托特股份有限公司 2024-03-29 CN claimed
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 US claimed
CN-117486883-A Purinyl fluorescent probe EDPH and application thereof in detection of content of hydrogen sulfide or Hela cell imaging 江苏科技大学 2024-02-02 CN claimed
CN-117088760-A Drug molecule for selectively inhibiting human breast cancer cells and application thereof 河北北方学院 2023-11-21 CN claimed
CN-116621826-A Epoxy monomer based on bicyclic acetal structure, and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2023-08-22 CN claimed
EP-1066269-A1 TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVES FOR TREATMENT OF HIV INFECTIONS JANSSEN PHARMACEUTICA N.V. (BE) 2001-01-10 EP claimed
EP-1054657-A1 AGENT FOR COLORING FIBERS Wella Aktiengesellschaft (DE) 2000-11-29 EP claimed
US-6150360-A ADMINISTERING TO A PATIENT SUFFERING FROM HUMAN IMMUNODEFICIENCY VIRUS INFECTION A TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVE JANSSEN PHARMACEUTICA N.V. (BE) 2000-11-21 US claimed
WO-2000033799-A1 AGENT FOR COLORING FIBERS WELLA AKTIENGESELLSCHAFT (DE) 2000-06-15 WO claimed
WO-1999050256-A1 TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVES FOR TREATMENT OF HIV INFECTIONS JANSSEN PHARMACEUTICA N.V. (BE) 1999-10-07 WO claimed
EP-0212095-B1 THERMOSETTABLE COMPOUNDS PREPARED FROM MONOHYDROXY AROMATIC ALDEHYDES AND METHYLATED PYRIDINES OR PYRAZINES THE DOW CHEMICAL COMPANY (US) 1989-09-06 EP claimed
EP-0212095-A1 Thermosettable compounds prepared from monohydroxy aromatic aldehydes and methylated pyridines or pyrazines THE DOW CHEMICAL COMPANY (US) 1987-03-04 EP claimed
EP-0193257-A1 Control of micro-organisms in water-containing compositions NIPA LABORATORIES, LTD. (GB) 1986-09-03 EP claimed
US-4600767-A Thermostable hydroxystyrylaza compounds THE DOW CHEMICAL COMPANY (US) 1986-07-15 US claimed
US-4578439-A Styryl pyridine cyanates, styryl pyrazine cyanates and polymers thereof THE DOW CHEMICAL COMPANY (US) 1986-03-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351586-B2 Thiophene[2,3-d]pyrimidine derivative DK6-1 and its preparation method and application CXCR6, TYMP, CDK6 CYP2C9 1575/4885CYP1A2 2619/4885CYP3A4 1057/4885
US-11957793-B2 Nanoparticles CBR3, CBR1, AKR1C3 CYP2C9 373/4885CYP1A2 281/4885CYP3A4 233/4885
US-11918671-B2 Multi-tone hair dyeing method in three steps TYR, HAO2, HAAO CYP2C9 1050/4885CYP1A2 650/4885CYP3A4 2007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.