Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.70 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709129 | 0.89 | ADORA2A (0.56) | ADORA2A | |
| SCHEMBL7705879 | 0.85 | ADORA2A (0.56) | ADORA2A | |
| SCHEMBL7478262 | 0.85 | ADORA2A (0.56) | ADORA2ATP53SMN1; SMN2 | |
| SCHEMBL7708420 | 0.84 | ADORA2A (0.51) | ADORA2A | |
| SCHEMBL7705841 | 0.83 | ADORA2A (0.56) | ADORA2A | |
| SCHEMBL7487756 | 0.83 | ADORA2A (0.56) | ADORA2APIK3R1PIK3CA | |
| SCHEMBL7705607 | 0.83 | NPC1 (0.52) | ADORA2ANPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL7709135 | 0.82 | ADORA2A (0.58) | ADORA2ASMN1; SMN2 | |
| SCHEMBL7711605 | 0.82 | ADORA2A (0.55) | ADORA2A | |
| SCHEMBL7486137 | 0.81 | ADORA2A (0.54) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |