SCHEMBL7708852

SCHEMBL7708852

CC(C)(C)OC(=O)c1ccccc1[S+](c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
TSHR P16473 2/20 0.38
HSD17B10 Q99714 1/20 0.38
ADRA1A P35348 1/20 0.37
ADRA1B P35368 1/20 0.37
GRM6 O15303 1/20 0.37
LMNA P02545 1/20 0.35
MEN1 O00255 1/20 0.35
NPC1 O15118 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34
MAPT P10636 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
GPR119 Q8TDV5 1/20 0.34
ACHE P22303 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29410052 0.86 GRM6 (0.35) ALDH1A1TDP1TSHRHSD17B10ADRA1A
SCHEMBL7708197 0.82 CA1 (0.31)
SCHEMBL29404461 0.81 TSHR (0.52) ALDH1A1TDP1TSHRHSD17B10LMNA
SCHEMBL3191597 0.81 TSHR (0.52) ALDH1A1TDP1TSHRHSD17B10LMNA
Hydrogen Peroxide SCHEMBL29048859 0.80 TSHR (0.48) ALDH1A1TDP1TSHRHSD17B10ADRA1A
SCHEMBL30111657 0.78 TSHR (0.50) ALDH1A1TDP1TSHRHSD17B10ADRA1A
SCHEMBL109178 0.78 TSHR (0.50) ALDH1A1TDP1TSHRHSD17B10ADRA1A
SCHEMBL31005144 0.78 TSHR (0.52) ALDH1A1TDP1TSHRHSD17B10LMNA
SCHEMBL3212516 0.78 TSHR (0.52) ALDH1A1TDP1TSHRHSD17B10LMNA
Trifluoromethanesulfonic Acid SCHEMBL5698051 0.77 ACHE (0.33) ALDH1A1GRM6ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6358665-B1 ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE CLARIANT INTERNATIONAL LTD. (CH) 2002-03-19 US disclosed