Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 17/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7711762 | 0.91 | ADORA2A (0.52) | ADORA2AADORA3ADORA1ADORA2BALDH1A1 | |
| SCHEMBL7709007 | 0.86 | ADORA2A (0.53) | ADORA2AADORA3ADORA1ADORA2BALDH1A1 | |
| SCHEMBL7711726 | 0.81 | ADORA2A (0.54) | ADORA2AADORA3ADORA1ALDH1A1HPGD | |
| SCHEMBL7703027 | 0.81 | ADORA2A (0.51) | ADORA2AADORA3ALDH1A1MAPTHPGD | |
| SCHEMBL7711685 | 0.79 | ADORA2A (0.57) | ADORA2AADORA3ADORA1ALDH1A1MAPT | |
| SCHEMBL7711750 | 0.79 | ADORA2A (0.57) | ADORA2AADORA3ADORA1ALDH1A1MAPT | |
| SCHEMBL7705853 | 0.79 | ADORA2A (0.53) | ADORA2AADORA3ADORA1ADORA2BALDH1A1 | |
| SCHEMBL7703196 | 0.79 | ADORA2A (0.53) | ADORA2AADORA3ADORA1ADORA2BALDH1A1 | |
| SCHEMBL7705907 | 0.78 | ADORA2A (0.56) | ADORA2AADORA3ADORA1ALDH1A1MAPT | |
| SCHEMBL7708987 | 0.78 | ADORA2A (0.48) | ADORA2AADORA3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |