Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 20/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 19/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714838 | 0.91 | ADRB3 (0.69) | ADRB2ADRB3ADRB1 | |
| SCHEMBL7714629 | 0.91 | ADRB3 (0.69) | ADRB2ADRB3ADRB1 | |
| SCHEMBL9272067 | 0.83 | ADRB2 (0.81) | ADRB2ADRB3ADRB1 | |
| SCHEMBL7716895 | 0.82 | ADRB3 (0.57) | ADRB2ADRB3ADRB1 | |
| SCHEMBL7708588 | 0.79 | ADRB3 (0.77) | ADRB2ADRB3ADRB1 | |
| SCHEMBL7708585 | 0.79 | ADRB3 (0.77) | ADRB2ADRB3ADRB1 | |
| SCHEMBL7714611 | 0.79 | ADRB3 (0.73) | ADRB2ADRB3ADRB1 | |
| SCHEMBL7712899 | 0.78 | ADRB3 (0.74) | ADRB2ADRB3ADRB1 | |
| SCHEMBL7712844 | 0.77 | ADRB3 (0.55) | ADRB2ADRB3ADRB1 | |
| SCHEMBL7714864 | 0.77 | ADRB3 (0.58) | ADRB2ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865421-B1 | ARYLETHANOLAMINE DERIVATIVES AND THEIR USE AS AGONISTS OF ATYPICAL BETA-ADRENOCEPTORS | GLAXO GROUP LTD (GB) | 2002-03-27 | — | — | EP | disclosed |
| US-6048872-A | DIETETICS; ANTIDIABETIC AGENTS; CARDIOVASCULAR DISORDERS; GASTROINTESTINAL DISORDERS | GLAXO WELLCOME INC. (US) | 2000-04-11 | — | — | US | disclosed |