Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.43 |
| ▸ | FUBP1 | Q96AE4 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709150 | 0.85 | ADORA2A (0.54) | ADORA2AALDH1A1L3MBTL1HPGDMEN1 | |
| SCHEMBL7708740 | 0.84 | ADORA2A (0.57) | ADORA2AALDH1A1L3MBTL1HPGDMEN1 | |
| SCHEMBL7708573 | 0.83 | ADORA2A (0.52) | ADORA2AALDH1A1L3MBTL1HPGDMEN1 | |
| SCHEMBL7708503 | 0.80 | NPC1 (0.53) | ADORA2AALDH1A1L3MBTL1HPGDMEN1 | |
| SCHEMBL7432234 | 0.80 | ADORA2A (0.56) | ADORA2AALDH1A1L3MBTL1HPGDMEN1 | |
| SCHEMBL7705947 | 0.78 | ADORA2A (0.54) | ADORA2AALDH1A1L3MBTL1HPGDMEN1 | |
| SCHEMBL7481723 | 0.78 | ADORA2A (0.53) | ADORA2A | |
| SCHEMBL7705888 | 0.78 | ADORA2A (0.49) | ADORA2AALDH1A1L3MBTL1HPGDMEN1 | |
| SCHEMBL7711758 | 0.77 | ADORA2A (0.50) | ADORA2AALDH1A1HPGDKDM4EHTT | |
| SCHEMBL7703024 | 0.77 | ADORA2A (0.49) | ADORA2AALDH1A1HPGDKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |