Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.61 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706160 | 0.92 | AGTR1 (0.65) | AGTR1AGTR2PPARG | |
| SCHEMBL7706141 | 0.87 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL7706065 | 0.84 | AGTR1 (0.64) | AGTR1AGTR2PPARG | |
| SCHEMBL7429975 | 0.83 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL7709126 | 0.83 | AGTR1 (0.62) | AGTR1AGTR2PPARG | |
| SCHEMBL8823642 | 0.83 | AGTR1 (0.65) | AGTR1AGTR2PPARG | |
| SCHEMBL7706154 | 0.83 | AGTR1 (0.60) | AGTR1AGTR2PPARG | |
| SCHEMBL7706142 | 0.82 | AGTR1 (0.61) | AGTR1AGTR2PPARG | |
| SCHEMBL7706157 | 0.82 | AGTR1 (0.61) | AGTR1AGTR2PPARG | |
| SCHEMBL7706159 | 0.80 | AGTR1 (0.68) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644188-B1 | Process for the preparation of sulfur derivatives of imidazole and intermediates obtained | AVENTIS PHARMA SA (FR) | 2002-12-04 | — | — | EP | claimed |
| EP-0648763-B1 | Process for the preparation of sulfur derivatives of imidazole and intermediates obtained | AVENTIS PHARMA SA (FR) | 2001-05-09 | — | — | EP | claimed |
| EP-0465368-B1 | Sulfur derivatives of imidazole, process for their preparation, intermediates, their use as medicaments, and pharmaceutical compositions containing them | HOECHST MARION ROUSSEL INC (FR) | 1998-05-20 | — | — | EP | claimed |