SCHEMBL770916

SCHEMBL770916

COC(=O)CCS(=O)(=O)Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.55
CA12 O43570 4/20 0.50
CA14 Q9ULX7 4/20 0.50
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 3/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
KDM4E B2RXH2 1/20 0.40
CA2 P00918 1/20 0.39
HSD17B10 Q99714 2/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
KAT2B Q92831 2/20 0.37
RECQL P46063 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28548757 0.98 TSHR (0.52) TSHRCA12CA14KMT2AMEN1
SCHEMBL1098601 0.86 TSHR (0.58) TSHRCA12CA14KMT2AMEN1
SCHEMBL19402824 0.85 TSHR (0.56) TSHRCA12CA14KMT2AMEN1
SCHEMBL19784710 0.83 TSHR (0.57) TSHRCA12CA14KMT2AMEN1
SCHEMBL30200780 0.83 TSHR (0.54) TSHRCA12CA14KMT2ALMNA
SCHEMBL1403393 0.83 TSHR (0.54) TSHRCA12CA14KMT2ALMNA
SCHEMBL1403149 0.83 TSHR (0.54) TSHRCA12CA14KMT2ALMNA
SCHEMBL19784553 0.81 TSHR (0.55) TSHRCA12CA14KMT2AMEN1
SCHEMBL1968935 0.78 TSHR (0.57) TSHRCA12CA14KMT2AMEN1
SCHEMBL4374105 0.78 TSHR (0.57) TSHRCA12CA14KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 325 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115806532-A Preparation method of impurities in MIT 大连百傲化学股份有限公司 2023-03-17 CN claimed
US-12612384-B2 Heterocyclic CYP4A inhibitor compounds and compositions thereof MBD Co., Ltd. (KR) 2026-04-28 US disclosed
US-20260092053-A1 KHK INHIBITORS GILEAD SCIENCES INC (US) 2026-04-02 US disclosed
EP-4146651-B1 SULFONYLAMIDINE SUBSTITUTED COMPOUNDS AND THEIR USE AS BETA-LACTAMASE INHIBITORS NINGXIA ACADEMY AGRICULTURE & FORESTRY SCIENCES (CN) 2026-03-04 EP disclosed
EP-4681774-A2 KHK INHIBITORS Gilead Sciences, Inc. (US) 2026-01-21 EP disclosed
EP-4313967-B1 KHK INHIBITORS GILEAD SCIENCES INC (US) 2025-11-12 EP disclosed
EP-4638441-A1 GLYCINE DERIVATIVES WITH P2X4 RECEPTOR-BLOCKING ACTIVITY AS DIAGNOSTICS AND FOR THE TREATMENT OF PAIN, INFLAMMATION, CANCER, AND OTHER P2X4 RECEPTOR-RELATED DISEASES Rheinische Friedrich-Wilhelms-Universität Bonn (DE) 2025-10-29 EP disclosed
US-12410160-B2 KHK inhibitors GILEAD SCIENCES, INC. (US) 2025-09-09 US disclosed
US-12410166-B2 Sulfonylamidine substituted compounds and their use as beta-lactamase inhibitors NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) 2025-09-09 US disclosed
EP-4157845-B1 PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES PFIZER (US) 2025-08-13 EP disclosed
EP-0698600-A1 Composition, method and test device for determining the presence of leukocyte cells, esterase or protease in a test sample Bayer Corporation (US) 1996-02-28 EP disclosed
US-5464739-A Urinalysis, hydrolysis of lactate ester BAYER CORPORATION (US) 1995-11-07 US disclosed
EP-0447013-B1 Fluorobenzene sulphonamides SCHERING AG (DE) 1994-08-03 EP disclosed
US-5210290-A NMR diagnostic aid SCHERING AKTIENGESELLSCHAFT (DE) 1993-05-11 US disclosed
EP-0447013-A1 Fluorobenzene sulphonamides SCHERING AKTIENGESELLSCHAFT (DE) 1991-09-18 EP disclosed
EP-0015442-B1 LOW-FOAMING CORROSION INHIBITORS WITH MICROBIOCIDAL PROPERTIES, THAT CONTAIN ALCANOLAMINE-BORIC ACID REACTION PRODUCTS AS THE ACTIVE INGREDIENTS BASF Aktiengesellschaft (DE) 1982-03-24 EP disclosed
US-4267122-A USEFUL AS CORROSION INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 1981-05-12 US disclosed
EP-0015442-A1 Low-foaming corrosion inhibitors with microbiocidal properties, that contain alcanolamine-boric acid reaction products as the active ingredients BASF Aktiengesellschaft (DE) 1980-09-17 EP disclosed
US-4126634-A CORROSION INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 1978-11-21 US disclosed
US-4060522-A ANTICORROSIVE BASF AKTIENGESELLSCHAFT (DT) 1977-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612384-B2 Heterocyclic CYP4A inhibitor compounds and compositions thereof CYP4A11, CYP4B1, CYP4A22 TSHR 2894/4885CA12 4240/4885CA14 3614/4885
US-20260092053-A1 KHK INHIBITORS KHK, SLC5A2, HK1 TSHR 2641/4885CA12 4596/4885CA14 4673/4885
US-12410166-B2 Sulfonylamidine substituted compounds and their use as beta-lactamase inhibitors MGAM, MGAM2, ABCC1 TSHR 2534/4885CA12 3565/4885CA14 3658/4885
US-12410160-B2 KHK inhibitors KHK, KHDRBS1, NADK TSHR 3789/4885CA12 4528/4885CA14 4444/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.