Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6433400 | 0.84 | CA12 (0.36) | CYP2D6CYP2C9ESR1CYP3A4ESR2 | |
| SCHEMBL6433023 | 0.84 | CA12 (0.36) | CYP2D6CYP2C9ESR1CYP3A4ESR2 | |
| SCHEMBL6433716 | 0.84 | CA12 (0.36) | CYP2D6CYP2C9ESR1CYP3A4ESR2 | |
| SCHEMBL7701150 | 0.82 | HTR2C (0.39) | HTR1AADRA2ASLC6A2SLC6A4CYP1A2 | |
| SCHEMBL7137900 | 0.78 | HTR2C (0.38) | HTR1AADRA2ASLC6A2SLC6A4CYP1A2 | |
| SCHEMBL7706184 | 0.75 | HCRTR2 (0.36) | HTR1AADRA2ASLC6A2SLC6A4CYP1A2 | |
| SCHEMBL20524226 | 0.75 | ESR2 (0.51) | CYP2D6CYP2C9ESR1CYP3A4ESR2 | |
| SCHEMBL8705847 | 0.75 | CNR2 (0.42) | HTR1AADRA2ASLC6A2SLC6A4CYP1A2 | |
| SCHEMBL7213445 | 0.73 | MAPT (0.44) | CYP1A2CYP3A4LMNA | |
| SCHEMBL18244622 | 0.71 | ESR2 (0.56) | CYP2D6CYP2C9ESR1CYP3A4ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165495-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000056702-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2000-09-28 | — | — | WO | disclosed |