Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 7/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6433400 | 1.00 | CA12 (0.36) | CA12CA1CA9ESR1ESR2 | |
| SCHEMBL6433023 | 1.00 | CA12 (0.36) | CA12CA1CA9ESR1ESR2 | |
| SCHEMBL6433948 | 0.85 | CA12 (0.39) | CA12CA1CA9CNR2POLB | |
| SCHEMBL6433944 | 0.85 | CA12 (0.39) | CA12CA1CA9CNR2POLB | |
| SCHEMBL6499011 | 0.85 | CA12 (0.39) | CA12CA1CA9CNR2POLB | |
| SCHEMBL6434515 | 0.85 | CA12 (0.39) | CA12CA1CA9CNR2POLB | |
| SCHEMBL7709254 | 0.84 | HTR1A (0.40) | ESR1ESR2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL5360778 | 0.83 | CA12 (0.39) | CA12CA1CA9CNR2PREP | |
| SCHEMBL5360774 | 0.83 | CA12 (0.39) | CA12CA1CA9CNR2PREP | |
| SCHEMBL5363897 | 0.83 | CA12 (0.39) | CA12CA1CA9CNR2PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165495-B1 | RESORCINOL DERIVATIVES | PFIZER (US) | 2005-04-20 | — | — | EP | disclosed |