Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709281 | 1.00 | MAPT (0.46) | MAPTALDH1A1LMNAATMHSP90AA1 | |
| SCHEMBL7717520 | 0.93 | MEN1 (0.50) | MAPTALDH1A1LMNAATMMEN1 | |
| SCHEMBL7717517 | 0.93 | MEN1 (0.50) | MAPTALDH1A1LMNAATMMEN1 | |
| SCHEMBL3412286 | 0.83 | MEN1 (0.50) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL10414500 | 0.81 | MEN1 (0.52) | MAPTALDH1A1LMNAATMMEN1 | |
| SCHEMBL10414502 | 0.81 | MEN1 (0.52) | MAPTALDH1A1LMNAATMMEN1 | |
| SCHEMBL7713241 | 0.80 | MAPT (0.40) | MAPTALDH1A1LMNAATMMEN1 | |
| SCHEMBL23609099 | 0.77 | RAB9A (0.49) | MAPTALDH1A1LMNAATMHSP90AA1 | |
| SCHEMBL28852575 | 0.77 | RAB9A (0.49) | MAPTALDH1A1LMNAATMHSP90AA1 | |
| SCHEMBL6677087 | 0.76 | MEN1 (0.71) | MAPTALDH1A1LMNAATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214326-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001018006-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |