Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | ADH4 | P08319 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30598359 | 1.00 | LMNA (0.56) | LMNAOPRM1TSHRTHRBSPHK1 | |
| SCHEMBL30598355 | 1.00 | LMNA (0.56) | LMNAOPRM1TSHRTHRBSPHK1 | |
| SCHEMBL30598349 | 1.00 | LMNA (0.56) | LMNAOPRM1TSHRTHRBSPHK1 | |
| SCHEMBL30598358 | 1.00 | LMNA (0.56) | LMNAOPRM1TSHRTHRBSPHK1 | |
| SCHEMBL28747885 | 1.00 | LMNA (0.56) | LMNAOPRM1TSHRTHRBSPHK1 | |
| SCHEMBL22471958 | 0.97 | LMNA (0.54) | LMNAOPRM1TSHRTHRBSPHK1 | |
| SCHEMBL3970370 | 0.97 | LMNA (0.54) | LMNAOPRM1TSHRTHRBSPHK1 | |
| SCHEMBL10732616 | 0.95 | LMNA (0.52) | LMNAOPRM1TSHRTHRBSPHK1 | |
| SCHEMBL28647647 | 0.93 | LMNA (0.50) | LMNAOPRM1TSHRTHRBSPHK1 | |
| SCHEMBL28901552 | 0.93 | LMNA (0.50) | LMNAOPRM1TSHRTHRBSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6361782-B1 | SKIN COMPOSITION | L'OREAL (FR) | 2002-03-26 | — | — | US | claimed |
| EP-1044673-B1 | Anhydrous cosmetic composition containing a dispersion of surface stabilized polymer particles | OREAL (FR) | 2001-07-11 | — | — | EP | claimed |
| US-6361782-B1 | SKIN COMPOSITION | L'OREAL (FR) | 2002-03-26 | — | — | US | disclosed |