Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA7 | P43166 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939260 | 0.89 | TSHR (0.55) | TSHRALDH1A1SMN1; SMN2CTSLCTSB | |
| SCHEMBL7950760 | 0.89 | TSHR (0.55) | TSHRALDH1A1SMN1; SMN2CTSLCTSB | |
| SCHEMBL6572035 | 0.85 | TSHR (0.73) | TSHRKDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL2749958 | 0.85 | TSHR (0.73) | TSHRKDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9083037 | 0.84 | TSHR (0.51) | TSHRALDH1A1MAPTKMT2ACAPN1 | |
| SCHEMBL7939268 | 0.84 | TSHR (0.55) | TSHRKDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9420155 | 0.84 | TSHR (0.55) | TSHRKDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9420215 | 0.83 | TSHR (0.50) | TSHRALDH1A1SMN1; SMN2CTSLCTSB | |
| SCHEMBL9420202 | 0.83 | TSHR (0.50) | TSHRALDH1A1SMN1; SMN2CTSLCTSB | |
| SCHEMBL7707081 | 0.80 | TSHR (0.53) | TSHRALDH1A1SMN1; SMN2ESR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988299-B1 | POLYMERISABLE, OPTICALLY ACTIVE DIOXOLANE DIESTERS | ROLIC AG (CH) | 2002-07-03 | — | — | EP | disclosed |
| US-6120859-A | Polymerisable, optically active dioxolane diesters | ROLIC AG (CH) | 2000-09-19 | — | — | US | disclosed |
| EP-0988299-A1 | POLYMERISABLE, OPTICALLY ACTIVE DIOXOLANE DIESTERS | Rolic AG (CH) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998055473-A1 | POLYMERISABLE, OPTICALLY ACTIVE DIOXOLANE DIESTERS | ROLIC AG (CH) | 1998-12-10 | — | — | WO | disclosed |