Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950760 | 1.00 | TSHR (0.55) | TSHRALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL7709533 | 0.89 | TSHR (0.54) | TSHRALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL6572035 | 0.87 | TSHR (0.73) | TSHRALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL2749958 | 0.87 | TSHR (0.73) | TSHRALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL9083037 | 0.86 | TSHR (0.51) | TSHRALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL7939268 | 0.86 | TSHR (0.55) | TSHRALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9420155 | 0.86 | TSHR (0.55) | TSHRALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9420215 | 0.84 | TSHR (0.50) | TSHRALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9420202 | 0.84 | TSHR (0.50) | TSHRALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2210689 | 0.83 | TSHR (0.79) | TSHRALDH1A1MAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3159388-B2 | — | — | 2001-04-23 | — | — | JP | claimed |
| EP-0515622-B1 | ORGANOLEPTIC COMPOSITIONS | GIVAUDAN ROURE INT (CH) | 1994-07-20 | — | — | EP | claimed |
| EP-0515622-A1 | ORGANOLEPTIC COMPOSITIONS. | GIVAUDAN ROURE INT (CH) | 1992-12-02 | — | — | EP | claimed |
| WO-1992010107-A1 | ORGANOLEPTIC COMPOSITIONS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1992-06-25 | — | — | WO | claimed |
| US-5371069-A | Organoleptic compositions | GIUAUDAN-ROURE CORPORATION (US) | 1994-12-06 | — | — | US | disclosed |
| EP-0515622-B1 | ORGANOLEPTIC COMPOSITIONS | GIVAUDAN ROURE INT (CH) | 1994-07-20 | — | — | EP | disclosed |
| EP-0515622-A1 | ORGANOLEPTIC COMPOSITIONS. | GIVAUDAN ROURE INT (CH) | 1992-12-02 | — | — | EP | disclosed |
| WO-1992010107-A1 | ORGANOLEPTIC COMPOSITIONS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1992-06-25 | — | — | WO | disclosed |