Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.52 |
| ▸ | CTSD | P07339 | 5/20 | 0.51 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710755 | 0.86 | BACE1 (0.44) | BACE1CTSDBACE2 | |
| SCHEMBL7715214 | 0.83 | BACE1 (0.57) | BACE1CTSDBACE2 | |
| SCHEMBL7709345 | 0.81 | BACE1 (0.46) | BACE1CTSDBACE2 | |
| SCHEMBL7712128 | 0.81 | BACE1 (0.68) | BACE1CTSDBACE2 | |
| SCHEMBL7712129 | 0.76 | BACE1 (0.41) | BACE1CTSDBACE2 | |
| SCHEMBL7711254 | 0.73 | BACE1 (0.75) | BACE1CTSDBACE2 | |
| SCHEMBL2571922 | 0.72 | BACE1 (0.84) | BACE1CTSDBACE2 | |
| SCHEMBL7707911 | 0.70 | BACE1 (0.88) | BACE1CTSDBACE2 | |
| SCHEMBL12592472 | 0.69 | BACE1 (0.65) | BACE1CTSDBACE2 | |
| SCHEMBL2571873 | 0.69 | BACE1 (1.00) | BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011130741-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-20 | — | — | WO | disclosed |