Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693879 | 0.75 | CTNNB1 (0.77) | CTNNB1MAPTIRAK4MEN1KMT2A | |
| SCHEMBL6653060 | 0.75 | CTNNB1 (0.53) | CTNNB1MAPTIRAK4MEN1KMT2A | |
| SCHEMBL6630067 | 0.73 | CTNNB1 (0.51) | CTNNB1MAPTIRAK4MEN1KMT2A | |
| SCHEMBL4155484 | 0.73 | CTNNB1 (0.74) | CTNNB1MAPTIRAK4MEN1KMT2A | |
| SCHEMBL4150117 | 0.73 | CHRM1 (0.57) | CTNNB1MAPTMEN1KMT2ANR1I2 | |
| SCHEMBL4142669 | 0.72 | CTNNB1 (0.67) | CTNNB1MAPTIRAK4MEN1KMT2A | |
| SCHEMBL30775031 | 0.72 | CTNNB1 (0.67) | CTNNB1MAPTIRAK4MEN1KMT2A | |
| SCHEMBL6629599 | 0.72 | CTNNB1 (0.53) | CTNNB1MAPTIRAK4MEN1KMT2A | |
| SCHEMBL6629908 | 0.71 | CTNNB1 (0.51) | CTNNB1MAPTIRAK4MEN1KMT2A | |
| SCHEMBL6632911 | 0.71 | CTNNB1 (0.51) | CTNNB1MAPTIRAK4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002016357-A2 | QUINUCLIDINE-SUBSTITUTED ARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS) | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-28 | — | — | WO | claimed |