Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28878570 | 0.82 | MGAM (0.36) | GAA | |
| SCHEMBL262119 | 0.82 | ALDH1A1 (0.44) | GAAALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL5745064 | 0.82 | GAA (0.42) | GAAALDH1A1HSD17B10LMNA | |
| SCHEMBL14150795 | 0.77 | GAA (0.34) | GAA | |
| Cyclopropane SCHEMBL20378311 | 0.77 | ALDH1A1 (0.40) | GAAALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL1728131 | 0.70 | ALDH1A1 (0.45) | GAAALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL423150 | 0.70 | ALDH1A1 (0.39) | GAAALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL4653162 | 0.69 | ALDH1A1 (0.43) | GAAALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL1417855 | 0.69 | ALDH1A1 (0.43) | GAAALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL7752776 | 0.69 | GAA (0.44) | GAAALDH1A1TSHRHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6361768-B1 | POLYMER FORMED BY COPOLYMERIZATION OF ANIONIC MONOMER HAVING CARBOXY-FUNCTIONAL GROUP, NON-QUATERNIZED CATIONIC MONOMER HAVING AMINO-FUNCTIONAL GROUP, NON-IONIC HYDROPHILIC MONOMER, HYDROPHOBIC MONOMER, OPTIONAL CROSSLINKING MONOMER | PMD HOLDINGS CORP. | 2002-03-26 | — | — | US | disclosed |
| EP-1147138-A1 | HYDROPHILIC AMPHOLYTIC POLYMER | The B.F. Goodrich Company (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000039176-A1 | HYDROPHILIC AMPHOLYTIC POLYMER | THE B.F. GOODRICH COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |