SCHEMBL7709824

SCHEMBL7709824

O=C(Cl)OCOC(=O)C1CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38
ADRB3 P13945 1/20 0.38
CHRM2 P08172 2/20 0.37
CHRM4 P08173 2/20 0.37
CHRM1 P11229 2/20 0.37
CHRM3 P20309 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7713705 0.98 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ACES2CES1
SCHEMBL393005 0.94 SMN1; SMN2 (0.39) ALDH1A1MEN1KMT2AADRB2ADRB1
SCHEMBL7715350 0.90 HPGD (0.35) ALDH1A1MEN1KMT2ASMN1; SMN2MAPT
SCHEMBL10099631 0.89 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ACES2CES1
SCHEMBL16573650 0.81 ALDH1A1 (0.47) ALDH1A1MEN1KMT2ACES2CES1
SCHEMBL7935177 0.80 ALDH1A1 (0.44) ALDH1A1MEN1KMT2ACES2CES1
SCHEMBL17928591 0.80 ALDH1A1 (0.47) ALDH1A1MEN1KMT2ACES2CES1
SCHEMBL7935181 0.80 ALDH1A1 (0.47) ALDH1A1MEN1KMT2ACES2CES1
SCHEMBL21343095 0.78 ALDH1A1 (0.42) ALDH1A1MEN1KMT2ACES2CES1
SCHEMBL26263772 0.78 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376548-B1 FUNGICIDES; HERBICIDES; INSECTICIDES ROHM AND HAAS COMPANY 2002-04-23 US disclosed
WO-2001056358-A2 ENHANCED PROPERTIED PESTICIDES ROHM AND HAAS COMPANY (US) 2001-08-09 WO disclosed