SCHEMBL7710158

SCHEMBL7710158

CC(C)(C)C(C(=O)OC(=O)C1CC2C=CC1C2)(C(=O)OC(=O)C1CC2C=CC1C2)C(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
ALDH1A1 P00352 7/20 0.40
HPGD P15428 1/20 0.38
POLB P06746 3/20 0.37
KMT2A Q03164 2/20 0.37
RAB9A P51151 1/20 0.36
APEX1 P27695 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35
ESR2 Q92731 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAPK1 P28482 1/20 0.34
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7710161 0.93 KDM4E (0.41) KDM4ELMNAALDH1A1HPGDPOLB
SCHEMBL2776891 0.87 LMNA (0.46) KDM4ELMNAALDH1A1HPGDPOLB
SCHEMBL2776167 0.81 LMNA (0.57) KDM4ELMNAALDH1A1HPGDPOLB
SCHEMBL14378676 0.81 LMNA (0.57) KDM4ELMNAALDH1A1HPGDPOLB
SCHEMBL2776488 0.81 LMNA (0.46) KDM4ELMNAALDH1A1HPGDPOLB
SCHEMBL7891625 0.78 LMNA (0.50) KDM4ELMNAALDH1A1HPGDPOLB
SCHEMBL22263912 0.78 KDM4E (0.46) KDM4ELMNAALDH1A1HPGDPOLB
SCHEMBL14534917 0.77 KDM4E (0.49) KDM4ELMNAALDH1A1HPGDPOLB
SCHEMBL30862606 0.77 KDM4E (0.49) KDM4ELMNAALDH1A1HPGDPOLB
SCHEMBL525537 0.77 KDM4E (0.49) KDM4ELMNAALDH1A1HPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376632-B1 NORBORNENE COMPOUND CONTAINING CARBOXY GROUPS HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-04-23 US disclosed
US-6265130-B1 COPOLYMERS OF BICYCLOALKENECARBONYLMALONATES HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2001-07-24 US disclosed