Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.32 |
| ▸ | CHRNG | P07510 | 1/20 | 0.32 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4192409 | 0.80 | TSHR (0.42) | TSHRFDPSALDH1A1MEN1LMNA | |
| SCHEMBL6103198 | 0.78 | TSHR (0.41) | TSHRFDPSALDH1A1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL27915254 | 0.78 | TSHR (0.41) | TSHRFDPSALDH1A1MEN1LMNA | |
| SCHEMBL4187442 | 0.77 | TSHR (0.44) | TSHRFDPSALDH1A1MEN1LMNA | |
| SCHEMBL21182545 | 0.69 | TSHR (0.40) | TSHRDPP7MAPTSLC6A2SLC6A3 | |
| SCHEMBL27915742 | 0.69 | FDPS (0.41) | FDPSALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL27462201 | 0.68 | TSHR (0.39) | TSHRMAPTNPSR1ABCB1 | |
| SCHEMBL18816164 | 0.67 | FDPS (0.33) | TSHRFDPSALDH1A1MEN1LMNA | |
| Cyclohexane SCHEMBL6963396 | 0.67 | TSHR (0.82) | TSHRALDH1A1LMNAMAPTPABPC1 | |
| SCHEMBL1461363 | 0.67 | FDPS (0.33) | TSHRFDPSALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6361940-B1 | IMMOBILIZATION; GENETIC ENGINEERING | QIAGEN GENOMICS, INC. | 2002-03-26 | — | — | US | disclosed |