Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.56 |
| ▸ | MAOB | P27338 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | CALML3 | P27482 | 1/20 | 0.52 |
| ▸ | SDHA | P31040 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 6/20 | 0.46 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710257 | 1.00 | MAOA (0.56) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL7710449 | 0.93 | MAOB (0.49) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL7710445 | 0.93 | MAOB (0.49) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL7710532 | 0.91 | MAOA (0.58) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL7710535 | 0.91 | MAOA (0.58) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL7160052 | 0.91 | F10 (0.56) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL7160049 | 0.91 | F10 (0.56) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL7710043 | 0.90 | MAOA (0.47) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL7710044 | 0.90 | MAOA (0.47) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL7710459 | 0.89 | F10 (0.48) | MAOAMAOBLMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362189-B1 | GRAMNEGATIVE, GRAMPOSITIVE BACTERIA | PHARMACIA AND UPJOHN COMPANY | 2002-03-26 | — | — | US | claimed |