Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Methylpiperidine SCHEMBL7712917 | 0.98 | ALDH1A1 (0.48) | ALDH1A1TSHRTP53CYP1A2TDP1 | |
| Trifluoroacetic Acid SCHEMBL2265470 | 0.80 | HRH4 (0.38) | ALDH1A1CYP1A2TDP1HTTLMNA | |
| Trifluoroacetic Acid SCHEMBL2265475 | 0.80 | HRH4 (0.38) | ALDH1A1CYP1A2TDP1HTTLMNA | |
| Trifluoroacetic Acid SCHEMBL931484 | 0.80 | HRH4 (0.38) | ALDH1A1CYP1A2TDP1HTTLMNA | |
| N-Methyl Pyrrolidine (Nmp) SCHEMBL9368873 | 0.78 | KDM4E (0.44) | ALDH1A1CYP1A2TDP1HTTLMNA | |
| N-Methyl Pyrrolidine (Nmp) SCHEMBL1687141 | 0.78 | CYP1A2 (0.50) | ALDH1A1CYP1A2TDP1HTTLMNA | |
| N-Methylpiperidine SCHEMBL2071509 | 0.78 | ALDH1A1 (0.38) | ALDH1A1CYP1A2TDP1HTTLMNA | |
| N-Methylpiperidine SCHEMBL2072770 | 0.78 | ALDH1A1 (0.38) | ALDH1A1CYP1A2TDP1HTTLMNA | |
| Trifluoroacetic Acid SCHEMBL2265017 | 0.78 | ALDH1A1 (0.38) | ALDH1A1CYP1A2TDP1HTTLMNA | |
| N-Methylpiperidine SCHEMBL2071510 | 0.78 | ALDH1A1 (0.38) | ALDH1A1CYP1A2TDP1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6361940-B1 | IMMOBILIZATION; GENETIC ENGINEERING | QIAGEN GENOMICS, INC. | 2002-03-26 | — | — | US | claimed |
| US-20250066860-A1 | METHODS AND MATERIALS FOR ASSESSING AND TREATING CANCER | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2025-02-27 | — | — | US | disclosed |
| US-12195803-B2 | Methods and materials for assessing and treating cancer | THE JOHNS HOPKINS UNIVERSITY (US) | 2025-01-14 | — | — | US | disclosed |
| US-20200377956-A1 | METHODS AND MATERIALS FOR ASSESSING AND TREATING CANCER | THE JOHNS HOPKINS UNIVERSITY | 2020-12-03 | — | — | US | disclosed |
| EP-3665308-A1 | METHODS AND MATERIALS FOR ASSESSING AND TREATING CANCER | The Johns Hopkins University (US) | 2020-06-17 | — | — | EP | disclosed |
| US-20190256924-A1 | METHODS AND MATERIALS FOR ASSESSING AND TREATING CANCER | THE JOHNS HOPKINS UNIVERSITY | 2019-08-22 | — | — | US | disclosed |
| WO-2019067092-A1 | METHODS AND MATERIALS FOR ASSESSING AND TREATING CANCER | THE JOHNS HOPKINS UNIVERSITY (US) | 2019-04-04 | — | — | WO | disclosed |
| US-6361940-B1 | IMMOBILIZATION; GENETIC ENGINEERING | QIAGEN GENOMICS, INC. | 2002-03-26 | — | — | US | disclosed |
| EP-0958378-A2 | COMPOSITIONS AND METHODS FOR ENHANCING HYBRIDIZATION SPECIFICITY | Rapigene, Inc. (US) | 1999-11-24 | — | — | EP | disclosed |
| EP-0952228-A2 | Compositions and methods for enhancing hybridization specificity | Rapigene, Inc. (US) | 1999-10-27 | — | — | EP | disclosed |
| WO-1998013527-A2 | COMPOSITIONS AND METHODS FOR ENHANCING HYBRIDIZATION SPECIFICITY | RAPIGENE, INC. (US) | 1998-04-02 | — | — | WO | disclosed |