Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12129057 | 0.79 | ALDH1A1 (0.67) | MAPTMEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL13016579 | 0.79 | MEN1 (0.48) | MAPTMEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL10567833 | 0.77 | MEN1 (0.56) | MAPTMEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL31231920 | 0.77 | MEN1 (0.56) | MAPTMEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL7530794 | 0.77 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1 | |
| SCHEMBL2317686 | 0.75 | MAPT (0.56) | MAPTMEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL222551 | 0.75 | ALDH1A1 (0.52) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL2813557 | 0.74 | MAPT (0.45) | MAPTMEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL2813556 | 0.74 | MAPT (0.45) | MAPTMEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL10328177 | 0.74 | MAPT (0.45) | MAPTMEN1KMT2ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | claimed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | disclosed |