Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.51 |
| ▸ | COMT | P21964 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.47 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.47 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | MPL | P40238 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.43 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29409575 | 0.97 | TTR (0.61) | TTRCYP1A2CTRB1COMTLDHA | |
| SCHEMBL703189 | 0.97 | TTR (0.61) | TTRCYP1A2CTRB1COMTLDHA | |
| Hydrochloric Acid SCHEMBL11157253 | 0.95 | TTR (0.59) | TTRCYP1A2CTRB1COMTLDHA | |
| SCHEMBL1121128 | 0.90 | TTR (0.72) | TTRCYP1A2CTRB1COMTAURKA | |
| SCHEMBL28290095 | 0.90 | TTR (0.72) | TTRCYP1A2CTRB1COMTAURKA | |
| SCHEMBL127423 | 0.90 | TTR (0.72) | TTRCYP1A2CTRB1COMTAURKA | |
| SCHEMBL2931657 | 0.89 | LDHA (0.68) | TTRCYP1A2CTRB1COMTLDHA | |
| Water SCHEMBL3919443 | 0.87 | TTR (0.69) | TTRCYP1A2CTRB1COMTAURKA | |
| Water SCHEMBL26654218 | 0.87 | TTR (0.69) | TTRCYP1A2CTRB1COMTAURKA | |
| SCHEMBL14699495 | 0.87 | TTR (0.48) | TTRCYP1A2CTRB1COMTLDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6361571-B1 | USING TAUTOMERIC NONOXIDATIVE DYES AND POLYMETHINE DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-26 | — | — | US | disclosed |