⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1170405 | 0.83 | — | — | |
| SCHEMBL2799546 | 0.80 | — | — | |
| SCHEMBL2801476 | 0.80 | — | — | |
| SCHEMBL10727564 | 0.76 | — | — | |
| SCHEMBL10343061 | 0.75 | ALDH1A1 (0.40) | — | |
| SCHEMBL10800089 | 0.75 | ALDH1A1 (0.37) | — | |
| SCHEMBL27705224 | 0.75 | ALDH1A1 (0.32) | — | |
| SCHEMBL11086030 | 0.74 | — | — | |
| SCHEMBL29898494 | 0.74 | — | — | |
| SCHEMBL8374965 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5604294-A | IMMUNOSUPRESSIVE, ANTIMICROBIAL, ANTIFUNGAL, ANTIVIRAL, ANTI-INFLAMMATORY AND ANTIPROLIFERATIVE ACTIVITY | ABBOTT LABORATORIES | 1997-02-18 | — | — | US | claimed |
| WO-1994021635-A1 | MACROCYCLIC IMMUNOMODULATORS | ABBOTT LABORATORIES (US) | 1994-09-29 | — | — | WO | claimed |
| US-8404860-B2 | Compound having hydantoin ring and method of producing the same | TOKUYAMA CORPORATION (JP) | 2013-03-26 | — | — | US | disclosed |
| US-8394573-B2 | Photoresist compositions and methods for shrinking a photoresist critical dimension | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-03-12 | — | — | US | disclosed |
| US-20120289705-A1 | COMPOUND HAVING HYDANTOIN RING AND METHOD OF PRODUCING THE SAME | SHIIGI HIROFUMI (JP) | 2012-11-15 | — | — | US | disclosed |
| US-8258313-B2 | Compound having hydantoin ring and method of producing the same | TOKUYAMA CORPORATION (JP) | 2012-09-04 | — | — | US | disclosed |
| US-20120070787-A1 | PHOTORESIST COMPOSITIONS AND METHODS FOR SHRINKING A PHOTORESIST CRITICAL DIMENSION | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-03-22 | — | — | US | disclosed |
| US-20100184993-A1 | COMPOUND HAVING HYDANTOIN RING AND METHOD OF PRODUCING THE SAME | TOKUYAMA CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| EP-2172459-A1 | COMPOUND HAVING HYDANTOIN RING AND METHOD OF PRODUCING THE SAME | Tokuyama Corporation (JP) | 2010-04-07 | — | — | EP | disclosed |
| US-5604294-A | IMMUNOSUPRESSIVE, ANTIMICROBIAL, ANTIFUNGAL, ANTIVIRAL, ANTI-INFLAMMATORY AND ANTIPROLIFERATIVE ACTIVITY | ABBOTT LABORATORIES | 1997-02-18 | — | — | US | disclosed |
| WO-1994021635-A1 | MACROCYCLIC IMMUNOMODULATORS | ABBOTT LABORATORIES (US) | 1994-09-29 | — | — | WO | disclosed |
| US-4496683-A | INCREASED SCORCH DELAY, FASTER CURE RATE AND IMPROVED REVERSION RESISTANCE | MONSANTO COMPANY (US) | 1985-01-29 | — | — | US | disclosed |
| EP-0104157-A1 | Rubber compositions containing a vulcanization system alterative | Monsanto Company (US) | 1984-03-28 | — | — | EP | disclosed |