Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.53 |
| ▸ | F10 | P00742 | 10/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | CALML3 | P27482 | 1/20 | 0.50 |
| ▸ | SDHA | P31040 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169812 | 0.93 | MAOA (0.52) | MAOAF10MAOBLMNAPTGS1 | |
| SCHEMBL7710555 | 0.93 | MAOA (0.52) | MAOAF10MAOBLMNAPTGS1 | |
| SCHEMBL5209849 | 0.91 | MAOA (0.64) | MAOAF10MAOBLMNAPTGS1 | |
| SCHEMBL5738893 | 0.90 | MAOA (0.54) | MAOAF10MAOBLMNAPTGS1 | |
| SCHEMBL5737909 | 0.89 | MAOB (0.52) | MAOAF10MAOBLMNAPTGS1 | |
| SCHEMBL6040232 | 0.88 | MAOA (0.54) | MAOAF10MAOBLMNAPTGS1 | |
| SCHEMBL6161441 | 0.88 | MAOA (0.53) | MAOAF10MAOBLMNAPTGS1 | |
| SCHEMBL14415830 | 0.87 | F10 (0.49) | MAOAF10MAOBLMNAPTGS1 | |
| SCHEMBL8168992 | 0.86 | MAOB (0.50) | MAOAF10MAOBLMNAPTGS1 | |
| SCHEMBL7702033 | 0.86 | F10 (0.53) | MAOAF10MAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254906-A1 | Tetrahydrothiopyran phenyloxazolidinone S,S-dioxides | PHARMACIA & UPJOHN COMPANY (US) | 2002-11-06 | — | — | EP | claimed |
| US-6083967-A | ANTIMICROBIAL AGENTS; ASSAY FOR DETERMINING THE INHIBITORY ACTIVITY OF OXAZOLIDINONES TO HUMAN MONOAMINE OXIDASE | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-04 | — | — | US | claimed |
| EP-1254906-A1 | Tetrahydrothiopyran phenyloxazolidinone S,S-dioxides | PHARMACIA & UPJOHN COMPANY (US) | 2002-11-06 | — | — | EP | disclosed |
| US-6265178-B1 | Assay for determining oxazolidinone antibiotics having minimum monoamine oxidase inhibitory activity | PHARMACIA & UPJOHN COMPANY | 2001-07-24 | — | — | US | disclosed |
| EP-1036074-A1 | S-OXIDE AND S,S-DIOXIDE TETRAHYDROTHIOPYRAN PHENYLOXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 2000-09-20 | — | — | EP | disclosed |
| US-6083967-A | ANTIMICROBIAL AGENTS; ASSAY FOR DETERMINING THE INHIBITORY ACTIVITY OF OXAZOLIDINONES TO HUMAN MONOAMINE OXIDASE | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-04 | — | — | US | disclosed |
| WO-1999029688-A1 | S-OXIDE AND S,S-DIOXIDE TETRAHYDROTHIOPYRAN PHENYLOXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 1999-06-17 | — | — | WO | disclosed |