Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.33 |
| ▸ | HTR7 | P34969 | 4/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16500059 | 0.78 | PTGS1 (0.47) | MEN1KMT2APTGS1PTGS2 | |
| SCHEMBL31525221 | 0.71 | AKR1B1 (0.40) | MEN1KMT2APTGS1PTGS2MGLL | |
| SCHEMBL31525220 | 0.71 | AKR1B1 (0.40) | MEN1KMT2APTGS1PTGS2MGLL | |
| Hydrochloric Acid SCHEMBL28493006 | 0.70 | GSK3A (0.36) | FAAHTP53CYP1A2CYP2C19PTGS1 | |
| SCHEMBL3694475 | 0.69 | PTGS1 (0.36) | KDM4EFAAHMEN1KMT2APTGS1 | |
| SCHEMBL20480820 | 0.68 | PTGS1 (0.41) | FAAHPTGS1PTGS2MGLL | |
| SCHEMBL28760071 | 0.68 | PTGS1 (0.43) | KDM4ESOAT1FAAHTP53MEN1 | |
| SCHEMBL5881215 | 0.68 | MGLL (0.52) | FAAHTP53PTGS1PTGS2MGLL | |
| SCHEMBL25363067 | 0.65 | MGLL (0.48) | FAAHTP53PTGS1PTGS2MGLL | |
| SCHEMBL19817136 | 0.64 | PTGS1 (0.72) | FAAHTP53PTGS1PTGS2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204428-A2 | TARGETED LIPID PARTICLES | Celltech R&D Limited (GB) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001012154-A2 | TARGETED LIPID PARTICLES | CELLTECH R&D LIMITED (GB) | 2001-02-22 | — | — | WO | disclosed |