SCHEMBL7710586

SCHEMBL7710586

CCCCc1cc(O)ccc1C.[SiH3]O[SiH3]

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.56
ALOX5 P09917 5/20 0.49
CYP3A4 P08684 3/20 0.49
TSHR P16473 2/20 0.49
TP53 P04637 2/20 0.49
HTT P42858 2/20 0.49
MEN1 O00255 1/20 0.49
MAPT P10636 1/20 0.49
ALOX15 P16050 1/20 0.49
KMT2A Q03164 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
ALDH1A1 P00352 2/20 0.43
GAA P10253 1/20 0.43
ERAP1 Q9NZ08 1/20 0.43
PTGS2 P35354 4/20 0.41
ESR1 P03372 3/20 0.40
ESR2 Q92731 1/20 0.40
RECQL P46063 1/20 0.40
ADRA2A P08913 2/20 0.38
ADORA3 P0DMS8 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60292 0.93 TYR (0.63) TYRALOX5CYP3A4TSHRTP53
SCHEMBL28332231 0.87 ALOX5 (0.62) TYRALOX5CYP3A4TSHRTP53
SCHEMBL11118608 0.86 ALOX5 (0.66) TYRALOX5CYP3A4TSHRTP53
SCHEMBL13913867 0.86 ALOX5 (0.66) TYRALOX5CYP3A4TSHRTP53
SCHEMBL13971494 0.81 CYP3A4 (0.52) TYRALOX5CYP3A4TSHRTP53
SCHEMBL20152935 0.78 TYR (0.48) TYRALOX5CYP3A4TSHRTP53
SCHEMBL330111 0.78 TYR (0.69) TYRALOX5CYP3A4TSHRTP53
SCHEMBL31553269 0.78 TYR (0.69) TYRALOX5CYP3A4TSHRTP53
SCHEMBL9339634 0.77 TYR (0.74) TYRALOX5CYP3A4TSHRTP53
Methoxymethane SCHEMBL5502961 0.77 TYR (0.67) TYRALOX5CYP3A4TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6352578-B1 Air cleaning filter, process for preparing the same, and high-level cleaner TAKASAGO THERMAL ENGINEERING CO., LTD. (JP) 2002-03-05 US disclosed