Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 8/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694548 | 1.00 | SIGMAR1 (0.38) | SIGMAR1POLBSMN1; SMN2CXCR4MEN1 | |
| SCHEMBL7708108 | 1.00 | SIGMAR1 (0.38) | SIGMAR1POLBSMN1; SMN2CXCR4MEN1 | |
| SCHEMBL7708139 | 0.86 | — | — | |
| SCHEMBL7708147 | 0.86 | — | — | |
| SCHEMBL7707623 | 0.77 | — | — | |
| SCHEMBL7707620 | 0.77 | — | — | |
| SCHEMBL7708132 | 0.77 | — | — | |
| SCHEMBL175418 | 0.76 | POLB (0.35) | SIGMAR1POLBSMN1; SMN2CXCR4MEN1 | |
| SCHEMBL7710736 | 0.76 | SMN1; SMN2 (0.35) | SIGMAR1POLBSMN1; SMN2CXCR4MEN1 | |
| SCHEMBL1481327 | 0.76 | POLB (0.35) | SIGMAR1POLBSMN1; SMN2CXCR4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359174-B1 | REACTING ALLYL REACTANT WITH ACID CHLORIDE IN PRESENCE OF LEWIS ACID CATALYST | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-03-19 | — | — | US | disclosed |