Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 4/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7715921 | 0.86 | FFAR4 (0.40) | DRD2CHRM4KCNA3DRD4DRD3 | |
| SCHEMBL7714679 | 0.85 | CHRM4 (0.49) | DRD2CHRM4KCNA3 | |
| SCHEMBL7716756 | 0.85 | DRD2 (0.51) | DRD2DRD3KDM4EEPHX1PIM1 | |
| SCHEMBL2464322 | 0.85 | KCNA3 (0.57) | DRD2KCNA3DRD3PIM1PIM3 | |
| SCHEMBL7932948 | 0.85 | OPRL1 (0.44) | DRD2KCNA3DRD4ALDH1A1EPHX1 | |
| SCHEMBL7930762 | 0.85 | OPRL1 (0.44) | DRD2KCNA3DRD4ALDH1A1EPHX1 | |
| SCHEMBL7936702 | 0.85 | OPRL1 (0.44) | DRD2KCNA3DRD4ALDH1A1EPHX1 | |
| SCHEMBL24986986 | 0.84 | CKS1B (0.56) | DRD2CHRM4DRD4DRD3KDM4E | |
| SCHEMBL7711061 | 0.84 | CHRM4 (0.48) | CHRM4KCNA3KDM4E | |
| SCHEMBL7716782 | 0.83 | DRD2 (0.69) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376503-B1 | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC | 2002-04-23 | — | — | US | disclosed |