Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.40 |
| ▸ | ITGAV | P06756 | 8/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6860649 | 1.00 | GAA (0.41) | GAAITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL6860791 | 0.95 | ITGB3 (0.41) | GAAITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7713835 | 0.95 | ITGB3 (0.41) | GAAITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL6860274 | 0.94 | ITGB3 (0.43) | GAAITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7708659 | 0.94 | ITGB3 (0.43) | GAAITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7711755 | 0.92 | GAA (0.39) | GAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6859135 | 0.90 | GAA (0.42) | GAAITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7708666 | 0.86 | GAA (0.40) | GAAITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL6862581 | 0.86 | GAA (0.40) | GAAITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7711485 | 0.86 | GAA (0.40) | GAAITGB3ITGAVITGA2BITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6794385-B2 | ANTITUMOR AGENTS; ANTICANCER AGENTS; OSTEOPOROSIS | PHARMACIA & UPJOHN, S.P.A. (IT) | 2004-09-21 | — | — | US | disclosed |
| US-6794385-B2 | ANTITUMOR AGENTS; ANTICANCER AGENTS; OSTEOPOROSIS | PHARMACIA & UPJOHN, S.P.A. (IT) | 2004-09-21 | — | — | US | disclosed |