SCHEMBL7711627

SCHEMBL7711627

CC1CC(=Cc2cc(N)ccc2Cl)C(=O)O1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 3/20 0.46
DYRK1B Q9Y463 3/20 0.46
CLK1 P49759 2/20 0.46
DYRK2 Q92630 2/20 0.43
PIK3CA P42336 1/20 0.43
MAOA P21397 7/20 0.37
MAOB P27338 3/20 0.37
ALDH1A1 P00352 1/20 0.35
HTT P42858 1/20 0.35
CREBBP Q92793 2/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
LMNA P02545 1/20 0.32
BRD4 O60885 1/20 0.32
XDH P47989 1/20 0.32
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
LDHA P00338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11303976 0.86 DYRK1A (0.48) DYRK1ADYRK1BCLK1DYRK2PIK3CA
SCHEMBL11831810 0.81 DYRK2 (0.51) DYRK1ADYRK1BCLK1DYRK2PIK3CA
SCHEMBL7711784 0.81 ALDH1A1 (0.48) DYRK1ADYRK1BCLK1DYRK2PIK3CA
SCHEMBL7713370 0.75 DYRK1A (0.39) DYRK1ADYRK1BCLK1DYRK2PIK3CA
SCHEMBL9520961 0.73 ALDH1A1 (0.47) DYRK1ADYRK1BCLK1DYRK2ALDH1A1
SCHEMBL14571667 0.70 DYRK1A (0.51) DYRK1ADYRK1BCLK1DYRK2PIK3CA
SCHEMBL5584115 0.70 DYRK1A (0.51) DYRK1ADYRK1BCLK1DYRK2PIK3CA
SCHEMBL11831579 0.69 DYRK1A (0.47) DYRK1ADYRK1BCLK1DYRK2PIK3CA
SCHEMBL981312 0.68 DYRK1A (0.69) DYRK1ADYRK1BCLK1DYRK2PIK3CA
SCHEMBL22694016 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE37664-E1 Use of derivatives of N-phenl-3,4,5,6-tetrahydrophthalimide for the desiccation and abscission of plant organs BASF AKTIENGESSELLSCHAFT (DE) 2002-04-16 US disclosed
EP-0385231-B1 Use of derivatives of N-phenyl-3,4,5,6-tetrahydrophthalimide in the desiccation and abscission of plant organs BASF AG (DE) 1996-09-18 EP disclosed
EP-0345637-B1 N-SUBSTITUTED 3,4,5,6-TETRAHYDROPHTHALIMIDE DERIVATIVES BASF Aktiengesellschaft (DE) 1993-03-17 EP disclosed
US-5045105-A Use of derivatives of n-phenyl-3,4,5,6-tetrahydrophthalimide for the desiccation and abscission of plant organs BASF AKTIENGESELLSCHAFT (DE) 1991-09-03 US disclosed
US-4959098-A HERBICIDES, PLANT GROWTH REGULATORS BASF AKTIENGESELLSCHAFT (DE) 1990-09-25 US disclosed
EP-0385231-A1 Use of derivatives of N-phenyl-3,4,5,6-tetrahydrophthalimide in the desiccation and abscission of plant organs BASF Aktiengesellschaft (DE) 1990-09-05 EP disclosed
EP-0345637-A1 N-substituted 3,4,5,6-tetrahydrophthalimide derivatives BASF Aktiengesellschaft (DE) 1989-12-13 EP disclosed