Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.53 |
| ▸ | MEN1 | O00255 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.45 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.45 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | PHGDH | O43175 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7711776 | 1.00 | MAPT (0.56) | MAPTPOLBPSMD14HTTKMT2A | |
| SCHEMBL7717340 | 0.88 | MAPT (0.56) | MAPTPOLBPSMD14HTTKMT2A | |
| SCHEMBL7717337 | 0.88 | MAPT (0.56) | MAPTPOLBPSMD14HTTKMT2A | |
| SCHEMBL7717334 | 0.88 | MAPT (0.56) | MAPTPOLBPSMD14HTTKMT2A | |
| SCHEMBL6950702 | 0.84 | ALDH1A1 (0.53) | MAPTPOLBHTTKMT2AMEN1 | |
| SCHEMBL6950703 | 0.84 | ALDH1A1 (0.53) | MAPTPOLBHTTKMT2AMEN1 | |
| SCHEMBL6950706 | 0.84 | ALDH1A1 (0.53) | MAPTPOLBHTTKMT2AMEN1 | |
| SCHEMBL7719398 | 0.84 | SMN1; SMN2 (0.42) | MAPTPOLBPSMD14HTTKMT2A | |
| SCHEMBL7719401 | 0.84 | SMN1; SMN2 (0.42) | MAPTPOLBPSMD14HTTKMT2A | |
| SCHEMBL7715612 | 0.82 | MAPT (0.57) | MAPTPOLBHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6379655-B1 | FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION | SOCIETE L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | claimed |
| US-6379655-B1 | FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION | SOCIETE L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | disclosed |