Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709762 | 0.89 | ACE (0.47) | ACECA1CA2TACR1LNPEP | |
| SCHEMBL28138297 | 0.84 | ACE (0.61) | ACECTSLTACR1CTSGCTRB1 | |
| SCHEMBL28138300 | 0.84 | ACE (0.61) | ACECTSLTACR1CTSGCTRB1 | |
| SCHEMBL7709445 | 0.80 | ACE (0.70) | ACELMNACTSLCA1CA2 | |
| SCHEMBL7513781 | 0.79 | PPARA (0.51) | ACECTSL | |
| SCHEMBL7046023 | 0.78 | ACE (0.60) | ACECTSLCA1CA2TACR1 | |
| SCHEMBL29452999 | 0.77 | ACE (0.55) | ACECTSLTACR1CTSGCTRB1 | |
| SCHEMBL3936009 | 0.77 | ACE (0.72) | ACELMNACTSLCA1CA2 | |
| SCHEMBL3936012 | 0.77 | ACE (0.72) | ACELMNACTSLCA1CA2 | |
| SCHEMBL5652507 | 0.76 | ACE (0.52) | ACELMNACTSLCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362165-B1 | Hydroxyphenyl derivatives with HIV integrase inhibitory properties | PHARMACOR INC. (CA) | 2002-03-26 | — | — | US | disclosed |