Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7712154 | 0.89 | ACE (0.51) | ACELNPEPKDM4EALDH1A1HPGD | |
| SCHEMBL7709356 | 0.86 | ACE (0.50) | ACELNPEPHPGDSF10PRSS1 | |
| SCHEMBL7511099 | 0.82 | ACE (0.64) | ACELNPEPHPGDSGPR132TACR1 | |
| SCHEMBL7523142 | 0.80 | ACE (0.50) | ACELNPEPHPGDSGPR132ERAP2 | |
| SCHEMBL28138300 | 0.78 | ACE (0.61) | ACEALDH1A1HPGDL3MBTL1F10 | |
| SCHEMBL28138297 | 0.78 | ACE (0.61) | ACEALDH1A1HPGDL3MBTL1F10 | |
| SCHEMBL7522184 | 0.76 | ATM (0.50) | ACELNPEPALDH1A1HPGDERAP2 | |
| SCHEMBL7553966 | 0.76 | GPR132 (0.58) | ACELNPEPHPGDSGPR132ERAP2 | |
| SCHEMBL7513781 | 0.75 | PPARA (0.51) | ACE | |
| SCHEMBL7703848 | 0.75 | GPR132 (0.63) | ACELNPEPHPGDSGPR132ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362165-B1 | Hydroxyphenyl derivatives with HIV integrase inhibitory properties | PHARMACOR INC. (CA) | 2002-03-26 | — | — | US | disclosed |