Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2052139 | 0.99 | HSD17B10 (0.61) | HSD17B10HPGDALOX15ALDH1A1KDM4E | |
| SCHEMBL11378484 | 0.90 | CYP3A4 (0.50) | HSD17B10HPGDALOX15ALDH1A1KDM4E | |
| SCHEMBL526114 | 0.82 | TDP1 (0.52) | HSD17B10HPGDALOX15ALDH1A1KDM4E | |
| SCHEMBL7614991 | 0.81 | HPGD (0.88) | HSD17B10HPGDALOX15ALDH1A1KDM4E | |
| SCHEMBL3883613 | 0.80 | HPGD (0.69) | HSD17B10HPGDALOX15ALDH1A1KDM4E | |
| SCHEMBL7712284 | 0.80 | KDM4E (0.55) | HSD17B10HPGDALOX15ALDH1A1KDM4E | |
| SCHEMBL24777597 | 0.80 | PTGS2 (0.68) | HSD17B10HPGDALOX15ALDH1A1KDM4E | |
| Phenyl Salicylate SCHEMBL9781104 | 0.79 | HPGD (0.73) | HSD17B10HPGDALOX15ALDH1A1KDM4E | |
| SCHEMBL1256105 | 0.79 | HSD17B10 (0.72) | HSD17B10HPGDALOX15ALDH1A1KDM4E | |
| SCHEMBL9472028 | 0.79 | HPGD (0.67) | HSD17B10HPGDALOX15ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104419502-A | Novel extreme-pressure anti-wear agent | ZHEJIANG DEZHONG ENERGY CO LTD | 2015-03-18 | — | — | CN | claimed |
| CN-104419502-A | Novel extreme-pressure anti-wear agent | ZHEJIANG DEZHONG ENERGY CO LTD | 2015-03-18 | — | — | CN | disclosed |
| US-6362136-B1 | MIXTURE OF WEAR RESISTANCE COMPOUND; HYDROCARBON MERCAPTAN AND OVERBASED COMPOUND | THE LUBRIZOL CORPORATION | 2002-03-26 | — | — | US | disclosed |
| EP-0684298-A2 | Compositions for extending seal life, and lubricants and functional fluids containing the same | The Lubrizol Corporation (US) | 1995-11-29 | — | — | EP | disclosed |