Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706413 | 0.83 | GAA (0.52) | GAALMNAL3MBTL1TP53USP2 | |
| SCHEMBL20539021 | 0.80 | KMT2A (0.53) | GAALMNAL3MBTL1TP53USP2 | |
| SCHEMBL7710351 | 0.80 | MAPT (0.67) | GAALMNAL3MBTL1TP53USP2 | |
| SCHEMBL8389573 | 0.78 | GAA (0.47) | GAALMNAL3MBTL1TP53USP2 | |
| SCHEMBL8389800 | 0.76 | MAPT (0.55) | GAALMNAL3MBTL1TP53USP2 | |
| SCHEMBL7710453 | 0.75 | MAPT (0.53) | GAALMNAL3MBTL1TP53USP2 | |
| SCHEMBL8385651 | 0.73 | MAPT (0.48) | GAALMNAL3MBTL1TP53USP2 | |
| SCHEMBL18269478 | 0.71 | RAD52 (0.53) | GAALMNAL3MBTL1TP53HSD17B10 | |
| SCHEMBL13325681 | 0.70 | RECQL (0.68) | LMNATP53HSD17B10KMT2AHTT | |
| SCHEMBL11962837 | 0.70 | HSD17B10 (0.64) | GAALMNAL3MBTL1TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | claimed |
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | disclosed |