Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385651 | 0.82 | MAPT (0.48) | GAAMAPTLMNAHSD17B10KMT2A | |
| SCHEMBL8389800 | 0.81 | MAPT (0.55) | GAAMAPTLMNAHSD17B10KMT2A | |
| SCHEMBL7712326 | 0.78 | GAA (0.70) | GAAMAPTLMNAHSD17B10KMT2A | |
| SCHEMBL7710351 | 0.77 | MAPT (0.67) | GAAMAPTLMNAHSD17B10KMT2A | |
| SCHEMBL15902304 | 0.74 | HPGD (0.36) | GAAMAPTLMNAHSD17B10MAPK1 | |
| SCHEMBL7710453 | 0.72 | MAPT (0.53) | GAAMAPTLMNAHSD17B10KMT2A | |
| SCHEMBL7706413 | 0.72 | GAA (0.52) | GAAMAPTLMNAHSD17B10KMT2A | |
| SCHEMBL20539021 | 0.72 | KMT2A (0.53) | GAAMAPTLMNAHSD17B10KMT2A | |
| SCHEMBL976753 | 0.66 | ALDH1A1 (0.44) | MAPTLMNAHSD17B10KMT2AMEN1 | |
| SCHEMBL7984951 | 0.64 | SMN1; SMN2 (0.33) | SMN1; SMN2NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994360-A | Fungicidal 5-alkyl-triazolopyrimidines | AMERICAN CYANAMID COMPANY (US) | 1999-11-30 | — | — | US | disclosed |