Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 2/20 | 0.42 |
| ▸ | PTPRB | P23467 | 2/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7720045 | 0.86 | ALDH1A1 (0.59) | ALDH1A1RECQLPKMKDM4ETHRB | |
| SCHEMBL7779924 | 0.85 | ALDH1A1 (0.71) | ALDH1A1RECQLPKMKDM4ETHRB | |
| SCHEMBL6770646 | 0.83 | ALDH1A1 (0.62) | ALDH1A1RECQLPKMKDM4ETHRB | |
| SCHEMBL11124323 | 0.82 | ALDH1A1 (0.78) | ALDH1A1RECQLPKMKDM4ETHRB | |
| SCHEMBL1494452 | 0.81 | ALDH1A1 (0.72) | ALDH1A1RECQLPKMKDM4ETHRB | |
| SCHEMBL6782409 | 0.80 | ALDH1A1 (0.76) | ALDH1A1RECQLPKMKDM4ETHRB | |
| SCHEMBL9556731 | 0.80 | ALDH1A1 (0.76) | ALDH1A1RECQLPKMKDM4ETHRB | |
| SCHEMBL9556830 | 0.79 | ALDH1A1 (0.74) | ALDH1A1RECQLPKMKDM4ETHRB | |
| SCHEMBL9849155 | 0.79 | ALDH1A1 (0.74) | ALDH1A1RECQLPKMKDM4ETHRB | |
| SCHEMBL8495876 | 0.79 | ALDH1A1 (0.74) | ALDH1A1RECQLPKMKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384014-B1 | ANTIBIOTICS AS BACTERICIDES | AVENTIS PHARMA S.A. (FR) | 2002-05-07 | — | — | US | disclosed |