Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL969537 | 0.89 | JAK2 (0.46) | PDK1MEN1KMT2ANPSR1EPHA2 | |
| SCHEMBL306377 | 0.89 | JAK2 (0.46) | PDK1MEN1KMT2ANPSR1EPHA2 | |
| SCHEMBL306376 | 0.89 | JAK2 (0.46) | PDK1MEN1KMT2ANPSR1EPHA2 | |
| SCHEMBL3643228 | 0.82 | MEN1 (0.46) | PDK1PTPN1CDC25BMEN1KMT2A | |
| SCHEMBL17823745 | 0.80 | PDK1 (0.49) | PDK1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL971720 | 0.80 | PDK1 (0.49) | PDK1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL17749375 | 0.79 | SMN1; SMN2 (0.50) | MEN1KMT2ANPSR1JAK2JAK1 | |
| SCHEMBL29335644 | 0.79 | MEN1 (0.55) | PDK1MEN1KMT2ANPSR1L3MBTL1 | |
| SCHEMBL21069485 | 0.78 | EPHA2 (0.52) | PDK1EPHA2GPR119ERBB2EPHB4 | |
| SCHEMBL30987068 | 0.78 | JAK2 (0.47) | JAK2JAK1GPR119LMNAPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011136192-A1 | IMIDAZO[1,2-a]PYRIDINE DERIVATIVE | アステラス製薬株式会社 (JP) | 2011-11-03 | — | — | WO | disclosed |