SCHEMBL7713616

SCHEMBL7713616

CC(O)Oc1ccc(CC(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.56
KDM4E B2RXH2 2/20 0.49
PTGS1 P23219 2/20 0.49
AKR1C3 P42330 1/20 0.49
AKR1C2 P52895 1/20 0.49
CA2 P00918 1/20 0.48
CAMK2A Q9UQM7 1/20 0.48
SRD5A2 P31213 2/20 0.47
AKR1B1 P15121 1/20 0.47
FFAR1 O14842 1/20 0.46
ALDH1A1 P00352 2/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46
ABCC4 O15439 1/20 0.46
LMNA P02545 1/20 0.46
GAA P10253 1/20 0.46
TSHR P16473 1/20 0.46
HTT P42858 1/20 0.46
PLA2G4B P0C869 1/20 0.44
CNR2 P34972 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL961317 0.87 POLB (0.73) POLBKDM4EPTGS1AKR1C3AKR1C2
SCHEMBL7153440 0.85 POLB (0.77) POLBKDM4EFFAR1LMNATSHR
SCHEMBL11300169 0.84 POLB (0.54) POLBKDM4EPTGS1AKR1C3AKR1C2
SCHEMBL22664487 0.84 POLB (0.54) POLBKDM4EPTGS1AKR1C3AKR1C2
SCHEMBL959202 0.84 POLB (0.54) POLBKDM4EFFAR1LMNATSHR
SCHEMBL8082302 0.82 POLB (0.53) POLBKDM4EPTGS1AKR1C3AKR1C2
SCHEMBL8081106 0.80 POLB (0.50) POLBKDM4EPTGS1AKR1C3AKR1C2
SCHEMBL4565148 0.80 FFAR1 (0.73) POLBSRD5A2AKR1B1FFAR1CNR2
SCHEMBL27662443 0.80 FFAR1 (0.73) POLBSRD5A2AKR1B1FFAR1CNR2
SCHEMBL27662594 0.80 FFAR1 (0.73) POLBSRD5A2AKR1B1FFAR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102531884-A Method for preparing 4-ethoxy phenylacetic acid HUBEI KANGJING BIOTECHNOLOGY CO LTD 2012-07-04 CN disclosed
US-6365172-B1 SELF-REINFORCED BIOABSORBABLE DEVICE COMPRISED OF FUSED OR SINTERED FIBERS MADE FROM BIOABSORBABLE POLYMER COMPRISING SPECIFIED POLYESTERAMIDE BIOAMIDE, INC. 2002-04-02 US disclosed
US-6120788-A Bioabsorbable triglycolic acid poly(ester-amide)s BIOAMIDE, INC. (US) 2000-09-19 US disclosed
US-4748169-A FLUOROPOLYMERS, PRINTED CIRCUITS DAINIPPON INK AND CHEMICALS, INC. (JP) 1988-05-31 US disclosed