Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7153440 | 0.84 | POLB (0.77) | POLBPARP10CNR2HTTTDP1 | |
| SCHEMBL7713616 | 0.84 | POLB (0.56) | POLBCNR2HTTFFAR1LMNA | |
| SCHEMBL108145 | 0.77 | CA2 (0.54) | LMNA | |
| SCHEMBL5433337 | 0.77 | LTA4H (0.47) | POLBPARP10LMNACYP1A2 | |
| SCHEMBL12667396 | 0.76 | POLB (0.71) | POLBPARP10CNR2LMNAKDM4E | |
| SCHEMBL10977168 | 0.76 | PARP10 (0.48) | POLBPARP10TDP1LMNACYP1A2 | |
| SCHEMBL97898 | 0.76 | PARP10 (0.48) | POLBPARP10TDP1LMNACYP1A2 | |
| SCHEMBL17961880 | 0.76 | PARP10 (0.48) | POLBPARP10TDP1LMNACYP1A2 | |
| SCHEMBL8361506 | 0.75 | PPARG (0.49) | POLBPARP10HTTLMNACYP1A2 | |
| SCHEMBL4725179 | 0.75 | TSHR (0.55) | POLBCNR2L3MBTL1CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8858998-B2 | Thermoresponsive arginine-based hydrogels as biologic carriers | CORNELL UNIVERSITY (US) | 2014-10-14 | — | — | US | disclosed |
| US-20110008441-A1 | THERMORESPONSIVE ARGININE-BASED HYDROGELS AS BIOLOGIC CARRIERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110008441-A1 | THERMORESPONSIVE ARGININE-BASED HYDROGELS AS BIOLOGIC CARRIERS | PARG, PNISR, PUF60 | POLB 3172/4885PARP10 1073/4885CNR2 835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.