SCHEMBL771362

SCHEMBL771362

CN(C)c1ccc(-c2ncc[nH]2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 2/20 0.63
MTOR P42345 1/20 0.57
ADK P55263 1/20 0.57
ALDH1A1 P00352 3/20 0.51
KDM4E B2RXH2 2/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP19A1 P11511 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
MAPT P10636 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
AURKA O14965 7/20 0.47
PDE3B Q13370 1/20 0.46
PDE3A Q14432 1/20 0.46
TCF4 P15884 1/20 0.43
CTNNB1 P35222 1/20 0.43
CCNB2 O95067 1/20 0.42
CDK1 P06493 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28382247 0.84 NISCH (0.62) NISCHMTORADKALDH1A1KDM4E
SCHEMBL722191 0.83 NISCH (0.78) NISCHMTORADKALDH1A1KDM4E
SCHEMBL27729601 0.81 NISCH (0.54) NISCHMTORADKALDH1A1KDM4E
SCHEMBL862114 0.81 NISCH (0.75) NISCHMTORADKALDH1A1KDM4E
SCHEMBL2903588 0.80 NISCH (0.58) NISCHMTORADKALDH1A1KDM4E
SCHEMBL674010 0.78 NISCH (1.00) NISCHMTORADKALDH1A1KDM4E
SCHEMBL8742944 0.78 CYP1A2 (0.43) NISCHMTORADKALDH1A1KDM4E
SCHEMBL27750051 0.77 NISCH (0.50) NISCHMTORADKALDH1A1KDM4E
Hydrochloric Acid SCHEMBL9357414 0.77 CYP1A2 (0.42) NISCHMTORADKALDH1A1KDM4E
SCHEMBL28230038 0.76 NISCH (0.96) NISCHMTORADKALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110791547-A Creatinine quantitative detection dry sheet for in vitro diagnosis 无锡锦帛诚医疗器械科技有限公司 2020-02-14 CN claimed
CN-101735217-A Application of imidazole [4,5-f][1,10] phenanthroline and derivative thereof to preparation of antineoplastic drug UNIV GUANGDONG PHARM 2010-06-16 CN claimed
CN-101379065-A Imidazopyridine derivatives inhibiting protein kinase activity, method for the preparation thereof and pharmaceutical composition containing same CRYSTALGENOMICS INC (KR) 2009-03-04 CN claimed
US-20250188072-A1 COMPOUNDS FOR TREATMENT OF CANCER UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2025-06-12 US disclosed
US-12187720-B2 Compounds for treatment of cancer UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2025-01-07 US disclosed
US-11465987-B2 Compounds for treatment of cancer Oncternal Therapeutics, Inc. (US) 2022-10-11 US disclosed
CN-114667097-A Glycated hemoglobin measurement 奥索临床诊断有限公司 2022-06-24 CN disclosed
US-20220024912-A1 COMPOUNDS FOR TREATMENT OF CANCER Oncternal Therapeutics, Inc. (US) 2022-01-27 US disclosed
US-11084811-B2 Compounds for treatment of cancer Oncternal Therapeutics, Inc. (US) 2021-08-10 US disclosed
CN-110791547-A Creatinine quantitative detection dry sheet for in vitro diagnosis 无锡锦帛诚医疗器械科技有限公司 2020-02-14 CN disclosed
EP-2608671-B1 COMPOUNDS FOR TREATMENT OF CANCER GTX INC (US) 2018-12-12 EP disclosed
CN-101107521-A Dry analysis element FUJIFILM CORP (JP) 2008-01-16 CN disclosed
EP-0999835-A4 IMIDAZOLE DERIVATIVES AS MDR MODULATORS ONTOGEN CORP (US) 2004-08-25 EP disclosed
EP-0999835-A1 IMIDAZOLE DERIVATIVES AS MDR MODULATORS Ontogen Corporation (US) 2000-05-17 EP disclosed
EP-0997527-A1 Stabilisation of peroxidases Ortho-Clinical Diagnostics (GB) 2000-05-03 EP disclosed
WO-1999002155-A1 IMIDAZOLE DERIVATIVES AS MDR MODULATORS ONTOGEN CORPORATION (US) 1999-01-21 WO disclosed
US-5840721-A INCREASE SENSITIVITY OF MULTIDRUG RESISTANT TUMOR CELLS TO ANTICANCER AGENTS ONTOGEN CORPORATION (US) 1998-11-24 US disclosed
US-5756527-A ANTICARCINOGENIC AGENTS ONTOGEN CORPORATION (US) 1998-05-26 US disclosed
EP-0577734-A1 CONTROLLED-RELEASE SOLID PHASE ASSAY DEVICE INCLUDING ENCAPSULATED REAGENTS FOR DETECTING CHEMICAL SUBSTANCES MICRO RESEARCH, INC. (US) 1994-01-12 EP disclosed
WO-1992017769-A1 CONTROLLED-RELEASE SOLID PHASE ASSAY DEVICE INCLUDING ENCAPSULATED REAGENTS FOR DETECTING CHEMICAL SUBSTANCES MICRO RESEARCH INC. (US) 1992-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12187720-B2 Compounds for treatment of cancer KLK3, BRDT, ACP3 NISCH 3272/4885MTOR 1294/4885ADK 2226/4885
US-11084811-B2 Compounds for treatment of cancer KLK3, BRDT, ACP3 NISCH 3272/4885MTOR 1294/4885ADK 2226/4885
US-20220024912-A1 COMPOUNDS FOR TREATMENT OF CANCER KLK3, BRDT, ACP3 NISCH 3272/4885MTOR 1294/4885ADK 2226/4885
US-20250188072-A1 COMPOUNDS FOR TREATMENT OF CANCER KLK3, BRDT, ACP3 NISCH 3272/4885MTOR 1294/4885ADK 2226/4885
US-11465987-B2 Compounds for treatment of cancer KLK3, BRDT, ACP3 NISCH 3272/4885MTOR 1294/4885ADK 2226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.