SCHEMBL8742944

SCHEMBL8742944

CCOc1cc(-c2ncc[nH]2)ccc1-c1ccc(N(C)C)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP19A1 P11511 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
VCP P55072 5/20 0.42
SMPD3 Q9NY59 1/20 0.41
NISCH Q9Y2I1 2/20 0.40
MAP3K11 Q16584 1/20 0.39
MAPK14 Q16539 1/20 0.38
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TLR9 Q9NR96 1/20 0.36
TLR8 Q9NR97 1/20 0.36
TLR7 Q9NYK1 1/20 0.36
CDK4 P11802 1/20 0.36
CCNA2 P20248 1/20 0.36
CCND1 P24385 1/20 0.36
CDK2 P24941 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9357414 0.99 CYP1A2 (0.42) CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9
Methyl Alcohol SCHEMBL10336693 0.96 VCP (0.42) CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9
Methylene Chloride SCHEMBL10337011 0.95 VCP (0.40) CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9
Acetic Acid SCHEMBL9357869 0.93 VCP (0.47) CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9
Acetic Acid SCHEMBL10336826 0.90 VCP (0.45) CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9
SCHEMBL6268221 0.82 SMPD3 (0.51) VCPSMPD3MAP3K11KDM4EALDH1A1
Hydrochloric Acid SCHEMBL9357721 0.81 SMPD3 (0.50) VCPSMPD3MAP3K11KDM4EALDH1A1
Acetic Acid SCHEMBL9357357 0.78 SMPD3 (0.47) VCPSMPD3MAP3K11KDM4EALDH1A1
SCHEMBL771362 0.78 NISCH (0.63) CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9
SCHEMBL27303149 0.73 VCP (0.49) CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0423784-B1 Dry analysis element for quantitative analysis of analyte contained in whole blood FUJI PHOTO FILM CO LTD (JP) 1997-01-02 EP disclosed