Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14685966 | 0.84 | PTGER4 (0.48) | GSK3BALDH1A1HPGDKDM4EHDAC3 | |
| SCHEMBL14685969 | 0.84 | PTGER4 (0.48) | GSK3BALDH1A1HPGDKDM4EHDAC3 | |
| SCHEMBL2901054 | 0.78 | MAOB (0.47) | HDAC6CYP1A2PDGFRBPDGFRA | |
| SCHEMBL14686076 | 0.78 | PTGER4 (0.41) | GSK3BLCKALDH1A1HPGDKDM4E | |
| SCHEMBL14686077 | 0.78 | PTGER4 (0.41) | GSK3BLCKALDH1A1HPGDKDM4E | |
| SCHEMBL19734612 | 0.78 | APP (0.70) | ALDH1A1HPGDKDM4EHDAC3HDAC4 | |
| SCHEMBL5522119 | 0.76 | LMNA (0.53) | KDM4EHDAC6CYP1A2 | |
| SCHEMBL2901494 | 0.76 | PPARG (0.45) | PPARG | |
| SCHEMBL28440296 | 0.76 | APP (0.61) | GSK3BLCKALDH1A1HPGDKDM4E | |
| SCHEMBL14686176 | 0.76 | PTGER4 (0.43) | GSK3BLCKALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376524-B1 | ANTIALLERGENS, ANTIHISTAMINES | SUNESIS PHARMACEUTICALS, INC. | 2002-04-23 | — | — | US | disclosed |