Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31641754 | 0.82 | MAPK1 (0.54) | GAAPOLBALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL7720927 | 0.81 | MAPK1 (0.52) | GAAPOLBALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL23244242 | 0.80 | ALDH1A1 (0.62) | POLBALDH1A1SMN1; SMN2PKMMAPK1 | |
| SCHEMBL23244240 | 0.80 | ALDH1A1 (0.62) | POLBALDH1A1SMN1; SMN2PKMMAPK1 | |
| SCHEMBL13645833 | 0.80 | CCR1 (0.66) | GAAPOLBALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL31639171 | 0.78 | P2RY12 (0.52) | POLBALDH1A1SMN1; SMN2PKMMAPK1 | |
| SCHEMBL31642259 | 0.78 | P2RY12 (0.52) | POLBALDH1A1SMN1; SMN2PKMMAPK1 | |
| SCHEMBL12422064 | 0.77 | MAPT (0.53) | GAAALDH1A1SMN1; SMN2PKMMAPT | |
| SCHEMBL13409018 | 0.76 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL7719163 | 0.76 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384063-B1 | Compound having effect of promoting neuron differentiation | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-0999204-A1 | NOVEL COMPOUND HAVING EFFECT OF PROMOTING NEURON DIFFERENTIATION | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-10 | — | — | EP | disclosed |